Most frequent microorganisms in skin infections at the General Provincial Hospital “Ambato”

Authors

DOI:

https://doi.org/10.37135/ee.04.09.05

Keywords:

Staphylococcus aureus, sensitivity, resistance, ecthyma

Abstract

Skin infections caused by microorganisms affect the skin and tissues directly, where they proliferate and cause serious alterations. These infections constitute a public health problem, since many microorganisms show resistance to common and uncommon antimicrobials, which directly affects the application of the appropriate treatment to the patient. This study aimed to identify the most frequent microorganisms in skin infections, their sensitivity and resistance to antibiotics in patients with infection who attended the General Provincial Hospital "Ambato" in the period from May 2017 to June 2018. The methodology used in this research is based on a descriptive, cross-sectional study with a qualitative-quantitative approach, using the documentary technique and the reporting of results as an instrument. The information was tabulated and analyzed using the Microsoft Office 2010. It was found that in 29% of the processed samples Staphylococcus aureus was isolated as the most frequent in this type of infections, with greater sensitivity to Clindamycin, Doxacillin and Linezolid (100%) and resistance to Penicillins and Oxacillin (47.82%). It is important to mention that 47.83% of the isolated S. aureus strains phenotypically expressed the mecA gene. The most frequent clinical entity associated with this type of infection was ecthyma with 55%. In conclusion, the resistance of strains to various antibiotics was verified, presenting the most relevant as resistant methicillin, resistant vancomycin and Klebsiella pneumoniae carbapenemases.

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References

Peralta R, Torres-de Taboada E. Infecciones de piel y partes blandas. Rev. virtual Soc. Parag Med Int. [Internet]. 2017 [citado 2019 Oct 18]; 4 (2):19-26. Disponible en: https://doi.org/10.18004/rvspmi/2312-3893

Batalla D, Maldonado F, Panfilo F, Rivero V, Sierra N, Pardo L, Koziol S. Caracterización de las infecciones de piel y tejidos blandos en niños de 0 a 14 años asistidos en el Departamento de Emergencia Pediátrica del Centro Hospitalario de Pereira Rosell. An Facultad Med. [Internet]. 2016 [citado 2019 Oct 18]; 3(1): 83-89. Disponible en: http://www.anfamed.edu.uy/index.php/rev/article/download/193/98

Raya M, Ferullo I, Arrizabalaga M, Nadal A, Díaz MP, Garau M, Payeras A. Infecciones cutáneas de tejidos blandos en pacientes hospitalizados: Epidemiología factores microbiológicos, clínicos y pronósticos. Enferm Infecc Microbiol Clin. [Internet]. 2014 [citado 2019 Nov 21]; 32(03): 23-28. Disponible en: https://doi.org/10.1016/j.eimc.2013.03.00

Boucher HW, Wilcox M, Talbot GH, Puttagunta S, Das AF, Dunne MW. Once-weekly dalbavancin versus daily conventional therapy for skin infection. N Engl J Med. [Internet]. 2014 [citado 2019 Sep 21]; 370(23): 2169-79. Disponible en: https://doi.org/10.1056/NEJMoa1310480.

Ong PY, Leung DY. Bacterial and viral infections in atopic dermatitis: a comprehensive review. Clin Rev Allergy Immunol. [Internet]. 2016 [citado 2019 Nov 28]; 51: 329–337. Disponible en: https://doi.org/10.1007/s12016-016-8548-5

Castaño-Jaramillo L, Beltrán-Arroyave C, Santander-Peláez LC, Vélez-Escobar AM, Garcés-Samudio CG y Trujillo-Honeysberg M. Características clínicas y microbiológicas de las infecciones de piel y tejidos blandos por Staphylococcus aureus en niños de un hospital en Medellín durante los años 2013 a 2015. Rev Chilena Infectol [Internet]. 2017 [citado 2019 Nov 16]; 34(5): 487-490. Disponible en: https://doi.org/10.4067/S0716-10182017000500487

Loza EH. Uso de antibióticos en infecciones de piel y partes blandas en niños de 1 a 5 años internados en el servicio de Infectología del Hospital Pediátrico Baca Ortiz, de la ciudad de Quito [Tesis en internet]. Quito: Universidad Central del Ecuador; 2017 [citado 2018 Agosto 05] Disponible en: http://www.dspace.uce.edu.ec:8080/bitstream/25000/11199/1/T-UCE-0006-020-2017.pdf.

Velasco J, Araque M, Araujo E, Longa A, Nieves B, Ramírez A, Sánchez K, Velazco E. Manual Práctico de Bacteriología Clínica. Mérida, Venezuela: Publicaciones Vicerrectorados Académico. 2008. CODEPRE.

Castellano-González MJ, Perozo-Mena AJ. Mecanismos de resistencia a antibióticos β-lactámicos en Staphylococcus aureus. Kasmera [Internet]. 2010 Jun [citado 2019 Jul 13]; 38(1): 18-35. Disponible en: http://ve.scielo.org/scielo.php?script=sci_arttext&pid=S0075-52222010000100003&lng=es.

Abente S, Carpinelli L, Guillén R, Rodríguez F, Fariña N, Laspina F, López Y. Frecuencia de Staphylococcus aureus meticilino resistente y del factor de virulencia PVL en pacientes ambulatorios con infección de piel y partes blandas de Asunción, Paraguay. Mem Inst Investig Cienc. [Internet]. 2016 [citado 2019 Oct 20]; 14(2): 8-16. Disponible en: https://doi.org/10.18004/Mem.iics/1812-9528/2016.014(02) 08-016.

Sánchez L, Pavas N, Rojas A, Pérez N. Infecciones por Staphylococcus aureus resistente a la meticilina adquirido en la comunidad en pacientes de Villavicencio, Colombia. Rev Cubana de Med Tropical [Internet]. 2016 [citado 2019 Mar 16]; 68(1): 40-50. Disponible en: http://www.revmedtropical.sld.cu/index.php/medtropical/article/view/125.

Arbolaez M, Rodríguez J, Lopez S, Gonzales G, Rodriguez R, Armas L. Staphylococcus aureus nosocomial de piel y tejidos blandos. Acta Méd del Centro. 2016; 10(4). Disponible en: http://www.revactamedicacentro.sld.cu/index.php/amc/article/view/758.

Macía-Rodríguez C, Alende-Castro V, Vazquez-Ledo L, Novo-Veleiro I, González-Quintela A. Skin and soft-tissue infections: Factors associated with mortality and re-admissions. Enferm Infecc Microbiol Clin [Internet]. 2017 [citado 2019 Nov 21]; 35(2): 76–81. Disponible en: https://doi.org/10.1016/j.eimc.2016.02.030.

Jung MY, Chung JY, Lee HY, Park J, Lee DY, Yang JM. Antibiotic susceptibility of Staphylococcus aureus in atopic dermatitis: current prevalence of methicillin-resistant Staphylococcus aureus in Korea and treatment strategies. Ann Dermatol. [Internet]. 2015 [citado 2019 Nov 21]; 27: 398–403. Disponible en: https://doi.org/10.5021/ad.2015.27.4.398.

Lim J, Park H, Cho S, Yooncorresponding H. Antibiotic Susceptibility and Treatment Response in Bacterial Skin Infection. Ann Dermatol. [Internet]. 2018 [citado 2019 Sep 21]; 30(2): 186–191. Disponible en: https://doi.org/10.5021/ad.2018.30.2.186

Park JM, Jo JH, Jin H, Ko HC, Kim MB, Kim JM, Kim DW, Jang HS, Kim BS. Change in Antimicrobial Susceptibility of Skin-Colonizing Staphylococcus aureus in Korean Patients with Atopic Dermatitis during Ten-Year Period. Ann Dermatol. [Internet]. 2016 [citado 2019 Nov 14]; 28 (4):470-8. Disponible en: https://doi.org/10.5021/ad.2016.28.4.470.

Kazimoto T, Abdulla S, Bategereza L, Juma O, Mhimbira F, Weisser M, Utzinger J, Von Müller L, Becker SL. Causative agents and antimicrobial resistance patterns of human skin and soft tissue infections in Bagamoyo, Tanzania. Acta Trop. [Internet]. 2018 [citado 2019 Nov 21]; 186: 102-106. Disponible en: https://doi.org/10.1016/j.actatropica.2018.07.007.

Escandón-Vargas K, Reyes S, Gutiérrez S, Villegas M V. The epidemiology of carbapenemases in Latin America and the Caribbean. Expert Rev Anti Infect Ther [Internet]. 2017 [citado 2019 Nov 21]; 15: 277-97. Disponible en: https://doi.org/10.1080/14787210.2017.1268918.

Candan ED, Aksöz N. Klebsiella pneumoniae: characteristics of carbapenem resistance and virulence factors. Acta Biochim Pol. [Internet]. 2015 [citado 2019 Nov 21]; 62 (4): 867-74. Disponible en: https://doi.org/10.18388/abp.2015_1148.

Goodman K E, Simner P J, Tamma P D, Milstone A M. Infection control implications of heterogeneous resistance mechanism in carbapenem-resistant Enterobacteriaceae (CRE). Expert Rev Anti Infect Ther [Internet]. 2016 [citado 2019 Sep 21]; 14: 1-14. Disponible en: https://doi.org/10.1586/14787210.2016.1106940.

Parruti G, Frattari A, Polilli E, Savini V, Sciacca A, Consorte A, Cibelli DC, Agostinone A, Di Masi F, Pieri A, Cacciatore P, Di Iorio G, Fazii P, Spina T. Cure of recurring Klebsiella pneumoniae carbapenemase-producing Klebsiella pneumoniae septic shock episodes due to complicated soft tissue infection using a ceftazidime and avibactam-based regimen: a case report. J Med Case Rep. [Internet]. 2019 [citado 2019 Oct 23]; 13(1):1-5. Disponible en: https://doi.org/10.1186/s13256-018-1934-2.

Brink AJ. Epidemiology of carbapenem-resistant Gram-negative infections globally. Curr Opin Infect Dis. [Internet]. 2019 [citado 2019 Sep 22]; 32(6):609-616. Disponible en: https://doi.org/10.1097/QCO.0000000000000608.

Vera-Leiva A, Barría-Loaiza C, Carrasco-Anabalón C, Lima C, Aguayo-Reyes A, Domínguez M, Bello-Toledo H, González-Rocha G. KPC: Klebsiella pneumoniae carbapenemasa, principal carbapenemasa en enterobacterias. Rev. chil. infectol. [Internet]. 2017 [citado 2019 Nov 21]; 34 (5): 476-484. Disponible en: https://doi.org/10.4067/S0716-10182017000500476.

Published

2020-07-15

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How to Cite

1.
Burbano Barreros LD, González Romero AC, Araujo Baptista LM, Cruz Tenempaguay RE. Most frequent microorganisms in skin infections at the General Provincial Hospital “Ambato”. REE [Internet]. 2020 Jul. 15 [cited 2024 Oct. 30];14(2):19-2. Available from: https://eugenioespejo.unach.edu.ec/index.php/EE/article/view/146

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