Enfermedad Ósea de Paget, reporte de caso clínico
DOI:
https://doi.org/10.37135/ee.04.24.07Keywords:
osteítis deformante, remodelación ósea, bifosfonatosAbstract
La enfermedad de Paget es un trastorno que afecta al metabolismo óseo dado por una remodelación ósea acelerada. Afecta principalmente a la pelvis, columna, huesos de extremidades inferiores y cráneo. Se cree que es el resultado de la combinación de factores genéticos y ambientales, su incidencia ha disminuido en los últimos años. Generalmente no se presentan síntomas; sin embargo, algunos refieren dolor óseo. El objetivo de tratamiento es evitar la remodelación ósea con el uso de bifosfonatos.
Se presenta caso de femenina de 34 años con dolor y deformidad ósea de rodilla de 5 meses de evolución, en radiografías y gammagrafía con signos compatibles con enfermedad de Paget. Se administra bifosfonatos con mejoría de cuadro a los 3 meses. Este es un caso relevante debido a que la incidencia de la enfermedad de Paget es mayor en hombres sobre los 40 años.
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